A.G. McArthur, N. Waglechner, F. Nizam, M.A. Azad, K. Bhullar, M.J. Canova, G. De Pascale, L. Ejim, L. Kalan, A.M. King, K. Koteva, M. Morar, J.S. O’Brien, A.C. Pawlowski, P. Spanogiannopoulos, A.D. Sutherland, I. Tang, P.L. Taylor, M. Thaker, W. Wang, M. Yan, T. Yu, & G.D. Wright. 2011. Towards a Comprehensive Antibiotic Resistance Database (CARD). Oral presentation at the Generic Model Organism Database Meeting, Ontario Institute for Cancer Research, Toronto, Canada.
Addressing the challenge of antibiotic resistance requires the combined efforts of researchers that span inquiry at the molecular, patient, and population levels. Yet, despite the common objective of finding solutions to drug resistance, practitioners of these research areas do not often integrate their research findings. This reality reflects the disparate investigative tools, timelines and specific project aims of these disciplines. Nevertheless, resistance genes and their products are the common elements that bridge antibiotic resistance research from bench to clinic to population. What is lacking in the field is a comprehensive database of resistance genes that includes molecular, clinical, and surveillance data that can serve to unify research. The Comprehensive Antibiotic Resistance Database (CARD) is a bioinformatic database of resistance genes, their products and associated phenotypes designed to address this need by combining a Drupal front-end, an ontological-centric design, GMOD's Chado schema, and the Gbrowse genome browser.
